Radio / Top 40 October 2021
| 1 | The Kid Laroi & Justin Bieber | Stay | MSR0921 |
| 2 | Ed Sheeran | Bad Habits | MSR0821 |
| 3 | Olivia Rodrigo | good 4 u | MSR0721 |
| 4 | Jack Lil Nas X & Harlow | INDUSTRY BABY | MSR0921 |
| 5 | Maneskin | Beggin | MSR0921 |
| 6 | Doja Cat | Kiss Me More | MSR0621 |
| 7 | Doja Cat | You Right | MSR0821 |
| 8 | Olivia Rodrigo | traitor | MSR1021 |
| 9 | The Weeknd | Take My Breath | MSR1021 |
| 10 | Lil Nas X | MONTERO (Call Me By Your Name) | MSR0521 |
| 11 | Doja Cat | Need To Know | MSR1021 |
| 12 | Ed Sheeran | Shivers | MSR1121 |
| 13 | Tai Verdes | A-O-K | MSR0721 |
| 14 | Dua Lipa | Love Again | MSR0821 |
| 15 | Walker Hayes | Fancy Like | MSR1021 |
| 16 | Shawn & Tainy Mendes | Summer Of Love | MSR1021 |
| 17 | Kane X Blackbear Brown | Memory | MSR0921 |
| 18 | Lil Nas X | That's What I Want | MSR1121 |
| 19 | Justin Bieber | Ghost | MSR1121 |
| 20 | Jonas Brothers | Who's In Your Head | MSR1121 |
Dance / Club October 2021
| 1 | Farruko x David Guetta | Pepas | RC1121 |
| 2 | Elton John & Dua Lipa | Cold Heart | MSC1021 |
| 3 | J Balvin & Skrillex f./Khaby Lame | In Da Getto | RC0921 |
| 4 | Shouse | Love Tonight | MSC0821 |
| 5 | Shane Codd f./Charlotte Haining | Always On My Mind | MSC0921 |
| 6 | Joel Corry x Jax Jones f./Charli XCX & Saweetie | Out Out | MSC1021 |
| 7 | DubVision & ANML KNGDM | I Wanna Be There | MSC0821 |
| 8 | Sigala & Rita Ora | You For Me | MSC0921 |
| 9 | Sofi Tukker & John Summit | Sun Came Up | MSC1121 |
| 10 | Tiesto & Karol G | Don't Be Shy | MSC1021 |
| 11 | Dillon Francis f./Bow Anderson | Reaching Out | MSC1021 |
| 12 | TELYKast With Sam Grey | Unbreakable | MSC1121 |
| 13 | Swedish House Mafia | It Gets Better | MSC1021 |
| 14 | Anabel Englund | Midnight Rapture | RC1121 |
| 15 | Topic x Bebe Rexha | Chain My Heart | MSC0821 |
| 16 | Sofi Tukker | Drinkee | MSC1021 |
| 17 | deadmau5 & Lights | When The Summer Dies | MSC0921 |
| 18 | Ed Sheeran | Bad Habits | MSC0921 |
| 19 | Yves Larock x Steff Da Campo f./Jaba | Rise Up | MSC1121 |
| 20 | Viiq | Heartless | MSC1021 |
Modern Rock October 2021
| 1 | Maneskin | Beggin | MRR1021 |
| 2 | Imagine Dragons | Wrecked | MRR0821 |
| 3 | Twenty One Pilots | Saturday | MRR0821 |
| 4 | Foo Fighters | Making A Fire | MRR0821 |
| 5 | Willow | t r a n s p a r e n t s o u l | MRR0621 |
| 6 | All Time Low | Monsters | MRR0720 |
| 7 | Vance Joy | Missing Piece | MRR0721 |
| 8 | Bastille | Distorted Light Beam | MRR0821 |
| 9 | Imagine Dragons | Follow You | MRR0521 |
| 10 | Walk The Moon | Can You Handle My Love?? | MRR0921 |
Urban Radio October 2021
| 1 | Drake | Way 2 Sexy | UR1121 |
| 2 | Wizkid | Essence | UR0921 |
| 3 | Yung Bleu | Baddest | UR0921 |
| 4 | Moneybagg Yo | Wockesha | UR0721 |
| 5 | Capella Grey | Gyalis | UR0921 |
| 6 | Bia | Whole Lotta Money | UR0721 |
| 7 | Normani | Wild Side | UR0921 |
| 8 | Roddy Ricch | Late At Night | UR0821 |
| 9 | Blxst | Chosen | UR0921 |
| 10 | Drake | Girls Want Girls | UR1121 |
Rhythm Radio October 2021
| 1 | Drake | Way 2 Sexy | RR1121 |
| 2 | Wizkid | Essence | RR0921 |
| 3 | Jack Lil Nas X & Harlow | INDUSTRY BABY | RR0921 |
| 4 | Pop Smoke | Woo Baby | RR0921 |
| 5 | Yung Bleu | Baddest | RR0821 |
| 6 | Doja Cat | You Right | RR0921 |
| 7 | Moneybagg Yo | Wockesha | RR0721 |
| 8 | The Kid Laroi & Justin Bieber | Stay | RR0921 |
| 9 | Doja Cat | Need To Know | RR1021 |
| 10 | Wale | Angles | RR0821 |
Country October 2021
| 1 | Lee Brice | Memory I Don't Mess With | CR0121 |
| 2 | Jason/Carrie Underwood Aldean | If I Didn't Love You | CR1021 |
| 3 | Jameson Rodgers | Cold Beer Calling My Name | CR0121 |
| 4 | Elvie Shane | My Boy | CR1120 |
| 5 | Walker Hayes | Fancy Like | CR0821 |
| 6 | Ryan W/Morris, Maren Hurd | Chasing After You | CR0421 |
| 7 | Old Dominion | I Was On A Boat That Day | CR0721 |
| 8 | Kenny Chesney | Knowing You | CR0521 |
| 9 | Zac Band Brown | Same Boat | CR0821 |
| 10 | Luke Combs | Cold As You | CR0921 |
Tropical October 2021
| 1 | Marc Anthony | Pa'lla Voy | TL1021 |
| 2 | Aventura & Bad Bunny | Volvi | TL0921 |
| 3 | Prince Royce | Lao' A Lao' | TL1021 |
| 4 | Farruko | Pepas | TL0821 |
| 5 | Ozuna | La Funka | TL1021 |
Regional October 2021
| 1 | Banda El Recodo De Cruz Lizarraga | Que Tienen Tus Palabras | RL0821 |
| 2 | Banda Los Sebastines & Los Rieleros Del Norte | El Columpio (Cuantas Veces Te Jije) | RL0921 |
| 3 | Calibre 50 | A La Antiguita | RL0721 |
| 4 | Banda Los Recoditos | Llorando En Un Carro Del Ano | RL1021 |
| 5 | La Maquina Nortena | Especial | RL1121 |
Pop October 2021
| 1 | Rauw Alejandro | Todo De Ti | PL0721 |
| 2 | J Balvin, Skrillex & Khaby Lame | In Da Getto | PL0821 |
| 3 | Enrique Iglesias f./Farruko | Me Pase | PL0821 |
| 4 | Bad Bunny | Yonaguni | PL0721 |
| 5 | Farruko X David Guetta | Pepas | PL1121 |
Caribbean October 2021
| 1 | Aventura & Bad Bunny | Volvi | CRB0921 |
| 2 | Daddy Yankee | Metele Al Perreo | CRB1021 |
| 3 | Ozuna | Este Loco | CRB0821 |
| 4 | Daddy Yankee, Myke Towers & Jhay | Subele El Volumen | CRB0921 |
| 5 | Tainy & Yandel | Deja vu | CRB0821 |
Video October 2021
| 1 | Walker Hayes | Fancy Like | CT0721 |
| 2 | Lil Nas X | Thats What I Want | UV1121 |
| 3 | Justin Bieber | Ghost | HV1121 |
| 4 | Farruko | Pepas | HV1121 |
| 5 | Marshmello & Jonas Brothers | Leave Before You Love Me | HV0721 |
| 6 | Olivia Rodrigo | good 4 u | HV0721 |
| 7 | Drake f./Future & Young Thug | Way 2 Sexy | UV1021 |
| 8 | Capella Grey | Gyalis | UV1021 |
| 9 | Doja Cat f./SZA | Kiss Me More | HV0521 |
| 10 | Tai Verdes | A-O-K | HV0721 |
| 11 | HD4PRESIDENT | Touch Down 2 Cause Hell | UV1021 |
| 12 | Ed Sheeran | Shivers | HV1121 |
| 13 | THE KID LAROI & Justin Bieber | Stay | HV0921 |
| 14 | Chloe | Have Mercy | HV1121 |
| 15 | Moneybagg Yo | Wockesha | UV1021 |
| 16 | bbno$ | Edamame | CL0921 |
| 17 | Coldplay x BTS | My Universe | HV1121 |
| 18 | Bia | Whole Lotta Money | UV0621 |
| 19 | Willow f./Travis Barker | t r a n s p a r e n t s o u l | HV0721 |
| 20 | Kacey Musgraves | Justified | CT1021 |